MicroRNAs in AKI and kidney transplantation

KJ Ledeganck, EM Gielis, D Abramowicz… - Clinical Journal of the …, 2019 - journals.lww.com
MicroRNAs are epigenetic regulators of gene expression at the posttranscriptional level.
They are involved in intercellular communication and crosstalk between different organs. As
key regulators of homeostasis, their dysregulation underlies several morbidities including
kidney disease. Moreover, their remarkable stability in plasma and urine makes them
attractive biomarkers. Beyond biomarker studies, clinical microRNA research in nephrology
in recent decades has focused on the discovery of specific microRNA signatures and the …